Uncertainty is abound in the international trade landscape. As the U.S. and ÃÛÌÇÖ±²¥ economies continue their recoveries, the breakdown of the global supply chain, rising prices, and the continued presence of COVID-19 remain headwinds against a return to normalcy. This publication of the ÃÛÌÇÖ±²¥ Business Review discusses these concerns with articles written by business and education leaders. The issue describes the unequal distribution of COVID-19 vaccines around the globe, the expansion of export potential in the ÃÛÌÇÖ±²¥ economy, the importance of free-trade agreements to growth and certainty in the economy, as well as the size and scope of ÃÛÌÇÖ±²¥ international trade.