Publications

  1. Leih, M., Plemel, R. L., West, M., Angers, C. G., Merz, A. J., & Odorizzi, G. (2024). Disordered hinge regions of the AP-3 adaptor complex promote vesicle budding from the late Golgi in yeast. Journal of Cell Science, jcs-262234.
  2. Wilson, Z. N., West, M., English, A. M., Odorizzi, G., & Hughes, A. L. (2024). Mitochondrial-derived compartments are multilamellar domains that encase membrane cargo and cytosol. Journal of Cell Biology, 223(11), e202307035.
  3. Suzuki, S. W., West, M., Zhang, Y., Fan, J. S., Roberts, R. T., Odorizzi, G., & Emr, S. D. (2024). A role for Vps13-mediated lipid transfer at the ER–endosome contact site in ESCRT-mediated sorting. Journal of Cell Biology, 223(4), e202307094.
  4. Ouyang, Y., Jeong, M. Y., Cunningham, C. N., Berg, J. A., Toshniwal, A. G., Hughes, C. E., Seiler, K., Van Vranken, J. G., Cluntun, A. A., Lam, G., Winter, J. M., Akdogan, E., Dove, K. K., Nowinski, S. M., West, M., Odorizzi, G., Gygi, S. P., Dunn, C. D., Winge, D. R., & Rutter, J. (2024). Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms. Elife, 13, e84282.
  5. Pfitzner, A. K., Zivkovic, H., Bernat-Silvestre, C., West, M., Peltier, T., Humbert, F., Odorizzi, G., & Roux, A. (2023). Vps60 initiates alternative ESCRT-III filaments. Journal of Cell Biology, 222(11).
  6. Buysse, D., West, M., Leih, M., and Odorizzi, G. (2022) Bro1 binds the Vps20 subunit of ESCRT-III and promotes ESCRT-III regulation by Doa4. Traffic 23(2):109-19.
  7. Wilson ZN, Buysse D, West M, Ahrens D, Odorizzi G. (2021) Vacuolar H+-ATPase dysfunction rescues intralumenal vesicle cargo sorting in yeast lacking PI(3,5)P2 or Doa4. J Cell Sci. 134(15):jcs258459.
  8. Tseng CC, Dean S, Davies BA, Azmi IF, Pashkova N, Payne JA, Staffenhagen J, West M, Piper RC, Odorizzi G, Katzmann DJ. (2021) Bro1 stimulates Vps4 to promote intralumenal vesicle formation during multivesicular body biogenesis. J Cell Biol. 220(8):e202102070.
  9. Plemel, R., Odorizzi, G., and Merz, A (2020) Genetically encoded multimode reporter of AP-3 traffic in budding yeast. Traffic 22(1-2):38-44.
  10. Buysse, D., West, M., Pfitzner, A.-K., Roux, A., and Odorizzi, G. (2020) The ubiquitin hydrolase Doa4 directly binds Snf7 to inhibit recruitment of ESCRT-III remodeling factors in S. cerevisiae. J. Cell Sci. 133(8):jcs241455.
  11. Wilson, Z.N., Scott, A.L., Dowell, R.D., and Odorizzi, G. (2018) PI(3,5)P2 controls vacuole potassium transport to support cellular osmoregulation. Mol. Biol Cell, 29:1718-31.
  12. Johnson, N., West, M., and Odorizzi, G. (2017) Regulation of yeast ESCRT-III membrane scission activity by the Doa4 ubiquitin hydrolase. Mol. Biol. Cell, 28:661-72.
  13. Odorizzi, G. (2015) Membrane manipulations by the ESCRT machinery. F1000Research 4 (F1000 Faculty Rev):516.
  14. Shideler ,T., Nickerson, D.P., Merz, A.J., & Odorizzi, G. (2015) Ubiquitin binding by the ÃÛÌÇÖ±²¥E domain promotes endosomal localization of the Rab5 GEF Vps9. Mol. Biol. Cell 26:1345-56.
  15. Mageswaran, S.K., Johnson, N.K., Odorizzi G.*, & Babst M.* (2015) Constitutively active ESCRT-II suppresses the MVB sorting phenotype of ESCRT-0 or ESCRT-I mutants. Mol. Biol. Cell 26:554-68.
  16. Odorizzi, G. (2014) ESCRTs take on a job in surveillance. Cell 159:240-41.
  17. Chi, R., Liu, J., West, M., Wang, J., Odorizzi, G., & Burd, C.G. (2014) Fission of SNX-BAR-coated endosomal retrograde transport carriers is promoted by the dynamin related protein Vps1. J. Cell Biol. 204:793-806.
  18. Richter, C.M., West, M., & Odorizzi, G. (2013) Doa4 function in ILV budding is restricted through its interaction with the Vps20 subunit of ESCRT-III.  J. Cell Sci. 126:1881-90.
  19. Babst, M., & Odorizzi, G. (2013) The balance of protein expression & degradation: an ESCRTs point of view.  Curr. Opin. Cell Biol. 25:489-94.
  20. Russell, M.R., Shideler, T., Nickerson, D.P., West, M., & Odorizzi, G. (2012) Class E compartments form in response to ESCRT dysfunction in yeast due to hyperactivity of the Vps21 GTPase.  J. Cell Sci. 125:5208-20.
  21. Wemmer, M., Azmi, I., West, M., Davies, B., Katzmann, D., & Odorizzi, G. (2011) Bro1 binding to Snf7 regulates ESCRT-III membrane scission activity in yeast.  J. Cell Biol. 192:295-306.
  22. McMurray, M.A., Stefan, C.J., Wemmer, M., Odorizzi, G., Emr, S.D., & Thorner, J. (2011) Genetic interactions with mutations affecting septin assembly reveal ESCRT functions in budding yeast cytokinesis.  Biol. Chem. 392:699-712.
  23. Kallay, L.M., Brett, C.L., Tukaye, D.N., Wemmer, M.A., Chyou, A., Odorizzi, G., & Rao, R. (2011) Endosomal Na+(K+)/H+ exchanger Nhx1/Vps44 functions independently & downstream of multivesicular body formation.  J. Biol. Chem. 286:44067-77.
  24. Nickerson, D.P., West, M., Henry, R., & Odorizzi, G. (2010) Regulators of Vps4 ATPase activity at endosomes differentially influence the size & rate of formation of intralumenal vesicles.  Mol. Biol. Cell 21:1023-32.
  25. Odorizzi, G., & Rehling, P. (2009) Membranes & organelles.  Curr. Opin. Cell Biol. 21:481-83.
  26. McNatt, M.W., McKittrick, I.B., West, M., & Odorizzi, G. (2007) Direct binding to Rsp5 mediates ubiquitin-independent sorting of Sna3 via the multivesicular body pathway. Mol. Biol. Cell. 18, 697-706.
  27. Richter, C.M., West, M., & Odorizzi, G. (2007) Dual mechanisms specify Doa4-mediated deubiquitination in the multivesicular body pathway.  EMBO J. 26, 2454-2464.
  28. Haas, T.J., Sliwinski, M.K., Martínez, D.E., Preuss, M., Ueda, T., Nielsen, E., Odorizzi, G., & Otegui, M.S. (2007) The Arabidopsis AAA ATPase SKD1 is involved in multivesicular endosome function & interacts with LIP5.  Plant Cell 19, 1295-1312.
  29. Nickerson, D.P., Russell, M.R.G., & Odorizzi, G. (2007) A concentric circle model of multivesicular body cargo sorting.  EMBO Rep. 8, 644-650.
  30. Odorizzi, G. (2006) The multiple personalities of Alix. J. Cell Sci. 19, 3025-32.
  31. Nickerson, D.P., West, M., & Odorizzi, G. (2006) Did2 coordinates Vps4-mediated dissociation of ESCRT-III from endosomes. J. Cell Biol, 175, 715-20.
  32. Russell, M.R.G., Nickerson, D.P., & Odorizzi, G. (2006) Molecular mechanisms of late endosome morphology, identity, & sorting. Curr. Opin. Cell Biol. 18, 422-28.
  33. Kim, J., Sitaraman, S., Hierro, A., Beach, B.M., Odorizzi, G., & Hurley, J.H. (2005) Structural basis for endosomal targeting by the Bro1 domain. Dev. Cell 8, 937-47.
  34. Luhtala, N., & Odorizzi, G. (2004) Bro1 coordinates deubiquitination in the multivesicular body pathway by recruiting Doa4 to endosomes. J. Cell Biol. 166, 717-29.
  35. Odorizzi, G., Katzmann, D.J., Babst, M., Audhya, A., Emr, S.D. (2003) Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae. J Cell Sci. 116, 1893-903.